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Learner Reviews & Feedback for Whole genome sequencing of bacterial genomes - tools and applications by Technical University of Denmark (DTU)

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1,475 ratings

About the Course

This course will cover the topic of Whole genome sequencing (WGS) of bacterial genomes which is becoming more and more relevant for the medical sector. WGS technology and applications are high on international political agenda, as the classical methods are being replaced by WGS technology and therefore bioinformatic tools are extremely important for allowing the people working in this sector to be able to analyze the data and obtain results that can be interpreted and used for different purposes. The course will give the learners a basis to understand and be acquainted with WGS applications in surveillance of bacteria including species identification, typing and characterization of antimicrobial resistance and virulence traits as well as plasmid characterization. It will also give the opportunity to learners to learn about online tools and what they can be used for through demonstrations on how to use some of these tools and exercises to be solved by learners with use of freely available WGS analysis tools . By the end of this course you should be able to: 1. Describe the general Principles in typing of Bacteria 2. Give examples of the applications of Whole Genome Sequencing to Surveillance of bacterial pathogens and antimicrobial resistance 3. Apply genomic tools for sub-typing and surveillance 4. Define the concept of Next-Generation Sequencing and describe the sequencing data from NGS 5. Describe how to do de novo assembly from raw reads to contigs 6. Enumerate the methods behind the tools for species identification, MLST typing and resistance gene detection 7. Apply the tools for species identification, MLST typing and resistance gene detection in real cases of other bacterial and pathogen genomes. 8. Describe the methods behind the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing 9. Utilize the tools for Salmonella and E.coli typing, plasmid replicon detection and plasmid typing in real cases of other bacterial and pathogen genomes. 10. Explain the concept and be able to use the integrated bacterial analysis pipeline for batch analysis and typing of genomic data 11. Demonstrate how to construct phylogenetic tree based on SNPs 12. Apply the phylogenetic tool to construct phylogenetic trees and explain the relatedness of bacterial or pathogen strains 13. Describe how to create your own sequence database 14. Utilize the MyDbFinder tool to detect genetic markers of interest from whole genome sequencing...

Top reviews

AM

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This is an interesting course. I do not have any prior knowledge of bioinformatics but I was able to understand with constant practice. Thank you DTU! Thank you, Coursera!!!

SP

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This course helped me a lot in determining bacterial typing. Just one question, in some quizzes I got some answers wrong so is there any way of knowing the right answer.

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226 - 250 of 393 Reviews for Whole genome sequencing of bacterial genomes - tools and applications

By Sonia R Q Q

Sep 16, 2019

a complete an interesting course, thanks!

By Md. A A

Jul 26, 2020

Its an awesome and very helpful course

By Shakil A S

Aug 31, 2020

Too much tough but still too amazing!

By Sharma

Nov 25, 2019

Great course. Excellent for research.

By Tavonga D Z

Jul 3, 2022

Great hands-on course. I enjoyed it.

By Dordia R

Jun 26, 2020

practical and clear. Really helpful!

By Deepak S

Apr 2, 2020

Excellent course, great instructors.

By Shahrzad H A

Oct 16, 2023

Great course and great instructors!

By Noor U

Aug 7, 2023

Thank You so much for your efforts.

By huma a

Jul 3, 2022

I have learnt alot from this course

By Eunice O

Sep 26, 2020

such an excellent practical course.

By Prince M

Oct 29, 2021

AMAZING COURSE THANK YOU VERY MUCH

By Tahir H

Dec 23, 2019

a good experience to get knowledge

By Jenny S

Jun 11, 2020

really helpful and awesome course

By Manaswini K

Jun 9, 2020

very useful ,thank you so much !!

By Rafael P

Jun 3, 2018

Great Course!, congratulations!

By IBRAHIM H A

Nov 9, 2019

This lecuers exterimly useful.

By Alida O

Sep 19, 2024

niveau de difficultés parfait

By Muhammad I

Sep 8, 2024

Well explained by the tutors

By Tanvi B

Jul 4, 2022

Very Informative and helpful

By 1806071

Sep 8, 2019

Very very informative course

By Katarina E

Mar 30, 2022

Very practical and useful!

By Pamela M

Apr 21, 2021

The best course about WGS!

By Mayur M

Jun 25, 2020

Very Clear and informative

By Alexandru B

Mar 25, 2018

very useful. thanks a lot.