This course focuses on the early stages of drug discovery and the identification of promising compounds with which to begin the hunt for a novel drug. Different types of assays and methods are reviewed that are used to screen libraries of molecules in the preliminary search for compounds with activity. Methods are discussed for validating that active molecules are indeed engaging a target associated with a predicted therapeutic benefit.
Targets, Assays & Screening
Targets, Assays & Screening
This course is part of Drug Hunting: The Science of Making New Medicines Specialization
Instructors: Erland Stevens, PhD
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Gain insight into a topic and learn the fundamentals.
4.8
(10 reviews)
Intermediate level
Recommended experience
8 hours to complete
3 weeks at 2 hours a week
Flexible schedule
Learn at your own pace
What you'll learn
Promising compounds used in the hunt for novel drugs. Types of assays & methods used to screen molecule libraries. Methods for hit validation.
Skills you'll gain
Details to know
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Assessments
12 assignments
Taught in English
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This course is part of the Drug Hunting: The Science of Making New Medicines Specialization
When you enroll in this course, you'll also be enrolled in this Specialization.
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There are 3 modules in this course
Welcome, by the end of the course students will be able to: Recognize the differences between target-based and phenotypic drug discovery. Differentiate between common library types and screening approaches for identifying small molecule hits. Describe some of the assay types used in early screening and factors to consider in their design.
What's included
5 videos2 readings3 assignments
What's included
5 videos3 readings6 assignments
What's included
5 videos2 readings3 assignments
Offered by
Recommended if you're interested in Research
Novartis
University of California San Diego
University of California San Diego
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