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There are 5 modules in this course
Biostatistics is the application of statistical reasoning to the life sciences, and it's the key to unlocking the data gathered by researchers and the evidence presented in the scientific public health literature. In this course, we'll focus on the use of simple regression methods to determine the relationship between an outcome of interest and a single predictor via a linear equation. Along the way, you'll be introduced to a variety of methods, and you'll practice interpreting data and performing calculations on real data from published studies. Topics include logistic regression, confidence intervals, p-values, Cox regression, confounding, adjustment, and effect modification.
Module one covers simple regression, the four different types of regression, commonalities between them, and simple linear aggression. Before completing the graded quiz, you can test your knowledge with the practice quiz.
What's included
8 videos2 readings2 assignments
Show info about module content
8 videos•Total 148 minutes
Introduction•3 minutes
Simple Regression: An Overview•17 minutes
Simple Linear Regression with a Binary (or Nominal Categorical) Predictor•14 minutes
Simple Linear Regression with a Categorical Predictor•22 minutes
Simple Linear Regression with a Continuous Predictor•26 minutes
Simple Linear Regression Model: Estimating the Regression Equation—Accounting for Uncertainty in the Estimates•26 minutes
Measuring the Strength of a Linear Association•23 minutes
Additional Examples•17 minutes
2 readings•Total 20 minutes
Solutions to Linear Regression Practice Quiz•10 minutes
Quiz 1 Solution•10 minutes
2 assignments•Total 30 minutes
Practice Quiz: Simple Linear Regression•0 minutes
Simple Linear Regression•30 minutes
Simple Logistic Regression
Module 2•3 hours to complete
Module details
Within module two, we will look at logistic regression, create confidence intervals, and estimate p-values. You will have the opportunity to test your knowledge in both a practice quiz and a graded quiz.
What's included
7 videos2 readings2 assignments
Show info about module content
7 videos•Total 114 minutes
Introduction•3 minutes
Simple Logistic Regression: An Overview•10 minutes
Simple Logistic Regression with a Binary (or Categorical) Predictor•23 minutes
Simple Logistic Regression with a Continuous Predictor•25 minutes
Simple Logistic Regression: Accounting for Uncertainty in the Estimates•16 minutes
Estimating Risk and Functions of Risk from Logistic Regression Results•17 minutes
Additional Examples•21 minutes
2 readings•Total 20 minutes
Solution Examples to Practice Quiz on Simple Logistic Regression•10 minutes
Quiz 2 Solutions•10 minutes
2 assignments•Total 30 minutes
Practice Quiz: Simple Logistic Regression•0 minutes
Logistic Regression•30 minutes
Simple Cox Proportional Hazards Regression
Module 3•3 hours to complete
Module details
Module three focuses on Cox regression with different predictors. You will have the opportunity to test your knowledge first with the practice quiz and, then, with the graded quiz.
What's included
7 videos2 readings2 assignments
Show info about module content
7 videos•Total 101 minutes
Introduction•2 minutes
Simple Cox Regression: An Overview•17 minutes
Simple Cox Regression with a Binary (or Categorical) Predictor•18 minutes
Simple Cox Regression with a Continuous Predictor•24 minutes
Simple Cox Regression: Accounting for Uncertainty in the Estimates•15 minutes
Estimating Survival Curves from Cox Regression Results•12 minutes
Additional Examples•14 minutes
2 readings•Total 25 minutes
Solutions for Practice Quiz on Simple Cox Regression•15 minutes
Solutions to Summative Quiz 3•10 minutes
2 assignments•Total 30 minutes
Practice Quiz: Simple Cox Proportional Hazards Regression•0 minutes
Simple Cox Regression•30 minutes
Confounding, Adjustment, and Effect Modification
Module 4•3 hours to complete
Module details
Within module four, you will look at confounding and adjustment, and unadjusted and adjusted association estimates. Additionally, you will learn about effect modification. Similar to previous modules, you will first take a practice quiz before completing the graded quiz.
What's included
10 videos1 reading2 assignments
Show info about module content
10 videos•Total 117 minutes
Introduction•1 minute
Confounding: A Formal Definition and Some Examples•16 minutes
Adjusted Estimates: Presentation, Interpretation, and Utility for Assessing Confounding•12 minutes
Adjusted Estimates: The General Idea Behind the Computations•8 minutes
Additional Examples•8 minutes
Effect modification: Introduction with an analytic example•17 minutes
Effect modification: Tree damage and elevation example•15 minutes
Effect modification: Examples from the literature•17 minutes
Confounding versus effect modification: A review•8 minutes
Additional examples•15 minutes
1 reading•Total 10 minutes
Solutions to Summative Quiz 4•10 minutes
2 assignments•Total 60 minutes
Practice Quiz: Confounding and Effect Modification•30 minutes
Confounding and Effect Modification•30 minutes
Course Project
Module 5•2 hours to complete
Module details
During this module, you get the chance to demonstrate what you've learned by putting yourself in the shoes of biostatistical consultant on two different studies, one about self-administration of injectable contraception and one about medical appointment scheduling in Brazil. The two research teams have asked you to help them interpret previously published results in order to inform the planning of their own studies. If you've already taken other courses in this specialization, then this scenario will be familiar.
What's included
1 reading1 assignment
Show info about module content
1 reading•Total 10 minutes
Biostatistical Consulting Project•10 minutes
1 assignment•Total 120 minutes
Course Project Quiz•120 minutes
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3 stars
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S
SR
5·
Reviewed on Dec 9, 2020
Complex analyses clearly explained, with an emphasis on interpretation rather than on mechanics. Excellent examples from published literature used throughout. Highly recommended!
A
AT
5·
Reviewed on Mar 21, 2023
Very happy that all I requested for was attended to i.e explanation especially of the summative assessment and others as required.Thank you so very much for making the learning impactful
P
PV
5·
Reviewed on Sep 5, 2020
Such complex concepts explained with ease. The section on confounding requires more than one reading. Really enjoyed it.
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What will I get if I subscribe to this Specialization?
When you enroll in the course, you get access to all of the courses in the Specialization, and you earn a certificate when you complete the work. Your electronic Certificate will be added to your Accomplishments page - from there, you can print your Certificate or add it to your LinkedIn profile.
Is financial aid available?
Yes. In select learning programs, you can apply for financial aid or a scholarship if you can’t afford the enrollment fee. If fin aid or scholarship is available for your learning program selection, you’ll find a link to apply on the description page.