Over 500,000 people in the United States and over 8 million people worldwide are dying from cancer every year. As people live longer, the incidence of cancer is rising worldwide, and the disease is expected to strike over 20 million people annually by 2030.
Understanding Cancer Metastasis
Understanding Cancer Metastasis
This course is part of Cancer Biology Specialization
Instructors: Kenneth J. Pienta, M.D.
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Gain insight into a topic and learn the fundamentals.
4.9
(2,428 reviews)
Beginner level
No prior experience required
Flexible schedule
Approx. 5 hours
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Assessments
6 quizzes
Taught in English
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This course is part of the Cancer Biology Specialization
When you enroll in this course, you'll also be enrolled in this Specialization.
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There are 6 modules in this course
In this first module, we'll concentrate on the history and overview of metastasis and give you a flavor of how cancer is defined as well as some of the history surrounding how we began to understand metastasis.
What's included
5 videos1 quiz
In this module, we'll focus on uncontrolled cell division, which is a defining property of cancer, as well as mutation and neoangiogenesis and their roles in tumor formation. We'll also take a look at a primary tumor microenvironment and its component cell types.
What's included
5 videos1 quiz
During this module, we'll turn our attention to the next steps after the initial primary tumor formation, epithelial to mesenchymal transition of cancer cells, and local tumor invasion and intravasation into blood or lymph vessels.
What's included
4 videos1 quiz
We'll now take a close look at cancer survival within the circulation, the role of the circulatory system in metastasis, the genetic determinants of metastatic potential, signalling mechanisms, chemokines, the dock and lock hypothesis, and extravasation.
What's included
6 videos1 quiz
In this module, we'll focus on dormancy and secondary tumor growth and how they contribute to the lethality of cancer.
What's included
6 videos1 quiz
In the previous modules, we've looked closely at the sequential steps of metastasis and some of the biology of how metastasis occurs. Now, we'll turn our attention to morbidity and mortality, or in other words, how cancer hurts and kills people.
What's included
4 videos1 quiz
Instructors
Instructor ratings
4.9 (592 ratings)Offered by
Recommended if you're interested in Basic Science
Johns Hopkins University
Universidad Nacional Autónoma de México
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Showing 3 of 2428
MS
5
Reviewed on May 10, 2023
I am delighted to complete this informative course. I wish to learn more from and be part of this team.
JJ
5
Reviewed on Sep 6, 2020
Thank you for the simple course structure and visual explanations. Having a background in Physics, I was able to quickly grasp the mechanisms on how cancer metastasizes.
MV
5
Reviewed on Sep 15, 2020
One of the best courses that I took! I am a premed student majoring in biology and I like the way the course was designed. They easily explained complex terms and processes.
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Frequently asked questions
Access to lectures and assignments depends on your type of enrollment. If you take a course in audit mode, you will be able to see most course materials for free. To access graded assignments and to earn a Certificate, you will need to purchase the Certificate experience, during or after your audit. If you don't see the audit option:
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